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. 2022 Jun 29;9:890314. doi: 10.3389/fnut.2022.890314

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Copyright © 2022 Tang, Wang, Jiang, Zhu, Zhang, Wang, Shu, Deng and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TY-S01 prevented loperamide-induced constipation in mice. (A) Body weight; (B) the time of the first black stool; (C) fecal water content; (D) intestinal advancement distance; (E) gastrointestinal transit rate; and (F) small intestinal sections stained with hematoxylin and eosin. NC is the normal control group; CM is the constipation model group; TY-S01 is the treatment group with TY-S01. ^# represents the significant difference between the NC and CM groups (p < 0.05); * represents the significant difference between the CM and TY-S01 groups (p < 0.05). Data are presented as mean ± SD.