Fig 3.

Risk of adverse safety outcomes comparing heterologous booster vaccine schedules of ChAdOx1-S priming and two mRNA booster doses with homologous mRNA booster vaccine schedules. Incidence rate ratios (IRRs) for the outcomes within 28 days were adjusted for calendar period, sex, birth year (proxy for age), region of residency, birth country, vaccine priority group, hospital contact in the past six months, and comorbidities. Cerebrovascular infarction includes non-haemorrhagic strokes and transient ischaemic attacks. Other bleeding events includes a composite of bleeding-related diagnoses other than intracranial haemorrhages. CI=confidence interval; NE=not estimated