Figure 4. Trends of Transcriptomic Metric Classifiers for the Likelihood of Bacterial or Viral Infection (IMX-BVN-3) Scores.

The crossover cohort included 11 patients considered to be at high risk who developed sepsis after admission to the surgical intensive care unit. A, Rise in IMX-BVN-3 scores peaking on the day of sepsis identification and then declining with subsequent intervention. B, Concurrent procalcitonin levels in the same patients. The trends (red lines) are presented using loess smoothing curves with 95% CIs (shaded regions). Dotted lines and points illustrate individual patient values.