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. 2022 May 13;9(7):ofac241. doi: 10.1093/ofid/ofac241

Table 1.

Association Between Clinical Characteristics of Diarrhea and Attribution to Adenovirus 40/41 vs Rotavirus and Other Viruses (Norovirus, Sapovirus, and Astrovirus)

Clinical Characteristics Adenovirus 40/41 Rotavirus Other Virusesa Adenovirus 40/41 vs Rotavirus, Adenovirus 40/41 vs Other Viruses,a
(n = 411) (n = 559) (n = 1122) aOR (95% CI)b aOR (95% CI)b
Age
 0–6 mo 83 (20.2) 112 (20.0) 105 (9.4) 1.25 (0.74–2.13) 3.58 (2.08–6.20)
 7–12 mo 153 (37.2) 228 (40.8) 394 (35.1) 1.02 (0.64–1.64) 1.64 (1.06–2.56)
 13–18 mo 116 (28.2) 143 (25.6) 397 (35.4) 1.20 (0.74–1.95) 1.41 (0.91–2.19)
 19–24 mo 59 (14.4) 76 (13.6) 226 (20.1) Referent Referent
Presence of blood in stool 17 (4.1) 12 (2.1) 27 (2.4) 1.82 (0.77–4.56) 1.34 (0.62–2.87)
Subjective fever 107 (26.0) 215 (38.5) 281 (25.0) 0.66 (0.49–0.91) 1.62 (1.16–2.26)
Duration of diarrhea episode, d 3.9 (2.8) 4.2 (3.1) 4.2 (3.4) 1.03 (0.97–1.09) 1.05 (0.99–1.10)
Maximum No. of loose stools 5.7 (2.5) 6.4 (3.0) 5.4 (2.1) 0.94 (0.89–0.99) 1.05 (0.99–1.12)
Presence of vomiting 137 (33.3) 272 (48.7) 331 (29.5) 0.66 (0.49–0.89) 1.34 (0.99–1.81)
Severe diarrhea (score >6) [4] 61 (14.8) 154 (27.6) 150 (13.4) 0.62 (0.43–0.90) 1.43 (0.94–2.17)
Dehydration (any) 33 (8.0) 94 (16.8) 106 (9.4) 0.60 (0.37–0.95) 1.22 (0.72–2.01)
Loss of appetite 134 (38.0) 144 (31.5) 286 (32.3) 0.84 (0.61–1.17) 0.87 (0.63–1.21)

Values shown are No. (%) for dichotomous variables and mean (SD) for continuous variables. Abbreviation: aOR, adjusted odds ratio.

a

Astrovirus, norovirus, and sapovirus.

b

Adjusted for site and attribution to Shigella or enterotoxigenic E. coli.