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Change of MMSE (A to C) and change of mMMSE (D to E) from 0 to 24 weeks. A and D show data from the full analysis set. B and E for participants with baseline MMSE < 25, and C and F for participants with baseline MMSE≥25. Modified MMSE (mMMSE) are calculated by abstracting Serial-7 from the eleven items of MMSE. Filled circle (MCC1274), open circle (placebo). †p < 0.1, *p < 0.05, significant difference from Placebo group (Wilcoxon rank-sum test).
