Neonatal	< 6 years	6–12 years	12–18 years	Adult
Detailed clinical examination, BP, screening for strabismus, kyphosis, scoliosis	X	X	X	X	X
Standard and Turner growth curves	X	X	X	X
FSH ± LH ± estradiol ± AMH	X FSH, LH	X FSH, LH	X E2, FSH, LH, AMH	X E2, FSH, LH, AMH	X E2, FSH, LH, AMH
TSH, ± FT4		> 4 years	X	X	X
Anti-TPO antibodies		> 4 years	X	X	X
HbA1c ± fasting blood glucose			X (> 10 years)	X	X
± fasting insulin (HOMA)
± OGTT		Before rhGH treatment if blood glucose and/or HbA1c levels are high	Before rhGH treatment if blood glucose and/or HbA1c levels are high	Before rhGH treatment if blood glucose and/or HbA1c levels are high
AST, ALT, Gamma-GT, alkaline phosphatase			X  > 6 years	X	X
IgA antitransglutaminases		X (> 2 years)	X	X	X As a function of symptoms
IgA total
Blood creatinine microalbumin/creatinine in urine	If renal malformation	If renal malformation or HT	If renal malformation or HT	If renal malformation or HT	If renal malformation or HT
Total cholesterol/HDLc/LDLc/triglycerides				X	X
CBC			X	X	X
25(OH)D		X	X	X	X
Thrombophilia panel				Before estrogen/estrogen-progesterone treatments if there are thromboembolic risk factors (in first-degree relative)	Before estrogen/estrogen-progesterone treatments if there are thromboembolic risk factors (in first-degree relative)
Cardiology consultation	X	X	X	X	X
Echocardiogram	X	X	X	X	X
Electrocardiogram	X	X	X	X	X
Aortic and cardiac MRI		As advised by the cardiologist	As advised by the cardiologist	As advised by the cardiologist	As advised by the cardiologist
Renal ultrasound	X	X	X	X	X
Thyroid ultrasound		If dysthyroidism or nodule	If dysthyroidism or nodule	If dysthyroidism or nodule	If dysthyroidism or nodule
Bone age		X	X	X
Pelvic ultrasound				After puberty	X
Bone densitometry				After puberty	X
ENT consultation and hearing assessment (adapted to age)		X	X	X	X
Ophthalmologic consultation	If suspicious signs	12–15 months and 3–4 yrs	If sensory or motor abnormality	If sensory or motor abnormality	If sensory or motor abnormality
Dental consultation ± panoramic X ray of dentition		If there is a clinical abnormality	X	X	X
Consultation with a dietitian		If overweight, carbohydrate intolerance, diabetes, dyslipidemia
Psychological consultation  ± psychometric tests	Parents, if necessary	X	X	X	X
Therapeutic education	Parents, if necessary	X	X	X	X