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. 2022 Jun 14;96(13):e00509-22. doi: 10.1128/jvi.00509-22

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Copyright © 2022 Lin et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 12 — Assessment of recognition and killing capabilities of SARS-CoV-2 membrane/ORF1ab-specific T cell clones. (A) Representative recognition and killing capabilities of SARS-COV-2-specific CD4⁺ and CD8⁺ T cell clones against peptide-pulsed, CFSE_Low target cells. (B) Percentage killing lysis at different effector/target ratios of CD4⁺ and CD8⁺ T cell clones. (C and D) Flow cytometry analysis of intracellular cytokines secretion of IFN-γ and GzmB by CD4⁺ and CD8⁺ T cell clones in the presence of peptide-pulsed target cells.