Table 2.
Decay in S1-Specific Immunoglobulin G Antibody Level per Study Group Assuming an Exponential Decay
| Variable | Control | Chronic Kidney Disease Stages 4/5 | Dialysis | Kidney Transplant Recipient |
|---|---|---|---|---|
| Half-life, days | 52.6 (43.2–65.5) | 52.4 (43.4–72.6) | 49.6 (40.4–63.5) | 52.9 (32.7–81.3) |
| Seroresponse defined as ≥10 BAU/mL at day 28, n (%) | 181 (100) | 152 (100) | 144 (100) | 154 (57.7) |
| S1 immunoglobulin G level (BAU/mL) in seropositive participants | 3009 (1812–4797) | 2380 (1267–4569) | 1587 (702–3121)a | 310 (57.1–1041)a |
| Time to 10 BAU/mL (days) in seropositive participants | 451 (378–569) | 442 (368–610) | 381 (313–494)a | 308 (119–473)a |
Variables are presented as mean ± standard deviation, as median (interquartile interval) in case of nonnormal distribution, or as number (percentage) in case of categorical data. P values were calculated using the Mann–Whitney U test with the control group as the reference group. Bonferroni correction was applied for multiple testing.
Abbreviation. BAU/mL, binding antibody units per milliliter.
P < .001.