Table 3.

ANC^* and ALC^† before and on G-CSF treatment

	Congenital			Cyclic		Autoimmune/Idiopathic
Age, yr	<18		≥18	<18	≥18	<18	≥18
Before G-CSF ANC	Median	0.2	0.2	0.4	0.5	0.2	0.4
	Mean	0.6	0.5	0.9	1.0	0.6	0.8
	SEM	(±0.05)	(±0.05)	(±0.07)	(±0.07)	(±0.04)	(±0.04)
	Range	(0-22.5)	(0-33.4)	(0-30.1)	(0-36.5)	(0-34.6)	(0-38.5)
Before G-CSF ALC	Median	4.9	2.9	4.7	2.2	4.1	1.5
	Mean	5.3	3.8	4.9	2.7	4.2	1.8
	SEM	(±0.13)	(±0.15)	(±0.1 9)	(±0.13)	(±0.10)	(±0.05)
	Range	(0.04-20.6)	(0.01-18.7)	(0.4-14.6)	(0.03-28.2)	(0.18-16.0)	(0.04-54.6)
G-CSF dosing (mcg/kg per day)	Median	4.8	3.5	2.1	1.6	1.5	0.8
	Mean	10.8	8.9	3.7	2.3	2.3	1.9
	SEM	(±1.04)	(±1.12)	(±0.69)	(±0.15)	(±0.13)	(±0.15)
	Range	(0.03-536.9)	(0.01-283.5)	(0.1-48.9)	(0.01-33.7)	(0.01-40.0)	(0.01-42.9)
After G-CSF ANC	Median	1.3	1.5	1.9	2.5	2.2	2.1
	Mean	2.6	3.3	4.0	5.2	3.9	3.7
	SEM	(±0.12)	(±0.14)	(±0.36)	(±0.29)	(±0.16)	(±0.13)
	Range	(0-76.7)	(0-107.5)	(0-63.3)	(0-91.7)	(0-120.1)	(0-199.0)
After G-CSF ALC	Median	3.7	2.3	3.8	2.1	3.5	1.7
	Mean	4.7	2.7	4.3	2.3	3.9	1.9
	SEM	(±0.12)	(±0.09)	(±0.22)	(±0.05)	(±0.10)	(±0.05)
	Range	(0.0-76.2)	(0.0-49.8)	(0.01-45.7)	(0.0-44.5)	(0.0-39.3)	(0.0-74.0)
G-CSF treatment, yr	Median	4.3	17.9	4.5	17.1	2.0	9.2
	Mean	5.3	16.9	5.4	16.3	3.2	10.7
	SEM	(±0.22)	(±0.52)	(±0.48)	(±0.70)	(±0.17)	(±0.37)
	Range	(0-17.6)	(0-31.4)	(0-16.6)	(0-32.2)	(0-15.9)	(0-30.8)

^*ANC = neutrophils × 10⁹/L.

^†ALC = lymphocytes × 10⁹/L.