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a. Senescent IEC6 cell model was established by H2O2 treatment. b. H2O2 did not induce IEC6 apoptosis by Flow cytometry analysis; c. H2O2 induced the expression of P21 and P16. d. The mRNA of IL-1β and IL-6 expression were increased in the senescent IEC6, n = 3. e. The cellular senescence model of FHs 74 (int intestinal cell line) was established. f. Evaluation of cell cycle and cell apoptosis.The asterisk indicates a significant difference (p < 0.05).
(Continued).
