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. 2022 Mar 31;21(14):1456–1467. doi: 10.1080/15384101.2022.2054636

Figure 6.

Figure 6.

Two-dimensional representation of proliferation P, quiescence Q and senescence S in normal cells.

Two-dimensional representation (proliferation rate vs geroconversion) distinguishes between Q and S in normal cell culture. In standard one-dimensional representation (proliferation rate), both Q and S would be just “proliferation arrest”. The model reveals reverse correlation between geroconversion and proliferation rate in normal proliferating cells.