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. Author manuscript; available in PMC: 2023 Jul 1.
Published in final edited form as: Radiat Res. 2022 Jul 1;198(1):89–105. doi: 10.1667/RADE-21-00224.1

Figure 8: Improved survival in mice with widespread ovarian cancer by delivery of chemotherapy with WAI and LR-IL-22.

Figure 8:

Mice with 2F8cis tumors received 15 Gy WAI, and paclitaxel (10 mg/kg), cisplatin (40 mg/kg) on day 3. Administration of LR-IL-22 gavage and WAI prior radiation fraction improves survival (p=0.0084). P values relative to tumor only. P<0.001 for ▼ compared to ■. Two-sided log-ranked test. ∧-Anti-PD-L1 alone after WAI. WAI was ineffective. (n=12 mice per group). Median survival for each group is shown in Table 4. Statistical evaluation was carried out using a two-sided log rank test.