Skip to main content
. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Cell Immunol. 2021 Aug 24;369:104426. doi: 10.1016/j.cellimm.2021.104426

Figure 4:

Figure 4:

Myeloid-derived suppressor cells derived from the peripheral blood mononuclear cells of adult participants with active TB disease express Toll-like Receptor 4 (TLR4). (a) The frequency of TLR4-expression on MDSC from active TB disease participants (n = 18) and healthy control participants (n = 10). (b) TLR4 expression on total MDSC (n = 18) and control monocyte populations (n = 12). (c) The median fluorescent intensity (MFI) of TLR4 expression on MDSC from participants with active TB disease compared to healthy control participants; as well as (d) the MFI of TLR4 expression on control monocytes and total MDSC. Frequencies were determined using the FACS Canto II flow cytometer, and the third-party software FlowJo. Error bars represent the median and range, while the whiskers represent the 5th-95th percentiles. ***P < 0.001; **P < 0.01; *P < 0.05; ns: not significant.