TABLE 3.
Binary logistic regression analyses of variables contributing to endothelial dysfunction (RHI < 1.67) in CKD patients
| Univariate logistic regression analysis | Multiple logistic regression analysis | |||||
|---|---|---|---|---|---|---|
| Wald χ 2 | P | OR (95% CI) | Wald χ 2 | P | OR (95% CI) | |
| Age (per 10 years) | 7.454 | .006 | 1.311 (1.079‐1.592) | 9.399 | .009 | 1.389 (1.126‐1.714) |
| Female | 3.652 | .056 | 0.604 (0.360‐1.013) | 5.038 | .025 | 0.536 (0.311‐0.924) |
| Current smoker | 0.107 | .743 | 0.903 (0.490‐1.664) | |||
| BMI (kg/m2) | 1.554 | .213 | 0.957 (0.892‐1.026) | |||
| SBP (mmHg) | 3.041 | .081 | 0.986 (0.971‐1.002) | |||
| DBP (mmHg) | 0.168 | .682 | 0.995 (0.973‐1.018) | |||
| Diabetes | 0.326 | .568 | 1.163 (0.693‐1.953) | |||
| eGFR (per 10 mL/min/1.73 m2) | 5.734 | .017 | 1.105 (1.018‐1.198) | |||
| Urine protein (g/day) | 1.733 | .188 | 0.935 (0.845‐1.034) | |||
| FBG (mmol/L) | 0.195 | .659 | 0.966 (0.829‐1.126) | |||
| TC (mmol/L) | 0.128 | .721 | 1.030 (0.878‐1.208) | |||
| TG (mmol/L) | 1.040 | .308 | 0.915 (0.771‐1.086) | |||
| HDL (mmol/L) | 3.207 | .073 | 1.666 (0.953‐2.913) | |||
| LDL (mmol/L) | 0.407 | .523 | 0.899 (0.885‐1.272) | |||
| Osteocalcin (per 10 ng/mL) | 8.170 | .004 | 0.789 (0.670‐0.928) | 7.707 | .006 | 0.794 (0.674‐0.934) |
| 25(OH)D (ng/mL) | 0.379 | .538 | 1.061 (0.978‐1.043) | |||
| PTH (pg/mL) | 5.251 | .022 | 0.992 (0.986‐0.999) | |||
| ACEI/ARB use | 0.678 | .900 | 1.191 (0.548‐1.478) | |||
| Antiplatelet use | 0.779 | .377 | 0.769 (0.429‐1.378) | |||
| Statins use | 1.679 | .195 | 0.721 (0.439‐1.183) | |||
Note: Age, sex, and other factors with P < .1 in univariate logistic regression were included in multiple logistic forward regression.