Table 4.
Adjusted* Cox modeling results for death, contingent on surviving to 1 year after LTx (reference group, BMI ⩾ 18.5 kg/m2 at LTx)
| Centers | HR | 95% CI | P Value |
|---|---|---|---|
| Including all centers, n = 1,733 with 783 deaths | |||
| 17–18.49 kg/m2 at LTx, BMI ⩾ 18.5 kg/m2 within 1 yr | 1.28 | (1.02–1.61) | 0.03 |
| 17–18.49 kg/m2 at LTx, no BMI ⩾ 18.5 kg/m2 in 1 yr | 1.72 | (1.14–2.59) | 0.01 |
| 17–18.49 kg/m2 at LTx, no BMI data in 1 yr | 0.62 | (0.44–0.86) | <0.01 |
| <17 kg/m2 at LTx, BMI ⩾ 18.5 kg/m2 within 1yr | 1.29 | (0.92–1.81) | 0.14 |
| <17 kg/m2 at LTx, no BMI ⩾ 18.5 kg/m2 in 1 yr | 1.57 | (1.09–2.25) | 0.02 |
| <17 kg/m2 at LTx, no BMI data in 1 yr | 0.93 | (0.66–1.31) | 0.69 |
| Sensitivity analysis omitting centers with post-transplant encounter data for <70% of recipients within 1 yr after LTx, n = 956 with 433 deaths | |||
| 17–18.49 kg/m2 at LTx, BMI ⩾ 18.5 kg/m2 within 1 yr | 1.15 | (0.88–1.52) | 0.31 |
| 17–18.49 kg/m2 at LTx, no BMI ⩾ 18.5 kg/m2 in 1 yr | 1.68 | (0.92–3.06) | 0.09 |
| 17–18.49 kg/m2 at LTx, no BMI data in 1 yr | 0.44 | (0.21–0.93) | 0.03 |
| <17 kg/m2 at LTx, BMI ⩾ 18.5 kg/m2 within 1 yr | 1.28 | (0.85–1.91) | 0.23 |
| <17 kg/m2 at LTx, no BMI ⩾ 18.5 kg/m2 in 1 yr | 1.48 | (0.94–2.32) | 0.09 |
| <17 kg/m2 at LTx, no BMI data in 1 yr | 1.10 | (0.65–1.87) | 0.72 |
Definition of abbreviations: BMI = body mass index; CI = confidence interval; HR = hazard ratio; LTx = lung transplant; N/A = not applicable.
*
Covariates include genotype (1–3, 4–5, N/A, other), age at transplant, insurance status at transplant (private, Medicaid, other), lung allocation score at transplant, transplant length of stay ⩾ 28 d, any documented insulin use by 1 year after LTx, and maximum recorded forced expiratory value in 1 second percentage during first year after LTx. Models stratified by LTx center.