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. 2022 Mar 16;13(3):7940–7950. doi: 10.1080/21655979.2022.2042142

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Phillyrin enhanced autophagy of H₂O₂-treated primary neuron cells. Western blot analysis showing the effects of phillyrin with different concentrations on mTOR (a), LC3 (b), and beclin-1 (c) in H₂O₂-treated neurons, and (d) the effects of ZSTK474 on the effects of phillyrin in H₂O₂-treated neurons. (e) LDH release from H₂O₂-treated neurons with different treatments. Note: n = 6; * P < 0.05 compared with the H₂O₂ group; **P < 0.01 compared with the H₂O₂ group; ^&&P < 0.01 compared with the phillyrin group; ^##P < 0.01 compared with the control group.