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. 2022 Mar 17;13(3):7367–7379. doi: 10.1080/21655979.2022.2040827

Figure 2.

Figure 2.

ZDHHC19 knockdown inhibited cell proliferation, invasion and migration in OS cells. (a, b) qRT-PCR and Western blot analysis of OS cells transfected with sh-ZDHHC19 or sh-NC. The ability of proliferation in OS cells transfected with sh-ZDHHC19 or sh-NC by CCK8 (c), EDU (d) and colony formation (e). (f) Analysis the effect of ZDHHC19 on the migration of 143B and MG63 cells by wound-healing assay. The ability of invasion and migration in OS cells transfected with sh-ZDHHC19 or sh-NC by transwell migration (g) and transwell invasion assay (h). (i) Expressions of migration-related proteins (MMP2, MMP7 and MMP9) in sh-ZDHHC19-transfected OS cells were detected by Western blot analysis. All data are presented as the mean ± standard deviation of three independent experiments. *P < 0.05; **P < 0.01.