Table 2.
Treatment | Pla | Sul | Toc | Sec | Ixe | Net | Bim | Ris | Ust | Fil | Tof | Upa | Eta | Inf | Ada | Cer | Gol |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RR (95% CI) for ASAS40 response | Reference | 1.18 (0.76, 1.82) | 0.60 (0.22, 1.67) | 1.87 (1.28, 2.73) | 2.41 (1.73, 3.34) | 2.22 (1.14, 4.32) | 3.44 (1.53, 7.76) | 1.50 (0.62, 3.63) | 0.90 (0.61, 1.33) | 2.00 (0.94, 4.23) | 1.72 (0.97, 3.03) | 2.02 (1.14, 3.59) | 2.25 (1.72, 2.94) | 3.63 (2.23, 5.91) | 2.44 (1.80, 3.31) | 3.58 (2.37, 5.39) | 2.52 (1.89, 3.38) |
SUCRA for ASAS40 response, % | 12.7 | 20.4 | 4.8 | 44.6 | 64.3 | 58.2 | 83.3 | 35.4 | 9.1 | 51.2 | 40.4 | 51.6 | 58.6 | 89.8 | 66.3 | 89.5 | 69.2 |
RR (95% CI) for incidence of SAEs | Reference | 1.05 (0.57, 1.96) | 1.00 (0.02, 49.45) | 0.56 (0.10, 3.07) | 0.20 (0.01, 2.72) | 2.78 (0.93, 8.30) | 1.00 (0.02, 48.28) | 1.97 (0.18, 21.13) | 0.14 (0.01, 2.68) | 0.95 (0.17, 5.27) | 3.00 (0.12, 72.15) | 0.33 (0.04, 3.04) | 0.67 (0.12, 3.94) | 0.33 (0.10, 1.04) | 2.18 (1.02, 4.68) | 3.99 (0.05, 322.63) | 0.55 (0.08, 3.67) |
SUCRA for incidence of SAEs, % | 49.0 | 54.1 | 16.8 | 64.9 | 62.8 | 49.3 | 81.7 | 66.9 | 71.6 | 27.5 | 67.4 | 48.4 | 39.6 | 54.4 | 32.8 | 23.2 | 39.5 |
RR: risk ratio; SMD: standardized mean difference; CIs: confidence intervals; SUCRA: surface under the cumulative ranking area; Pla: placebo; Sul: sulfasalazine; Toc: tocilizumab; Sec: secukinumab; Ixe: ixekizumab; Net: netakimab; Bim: bimekizumab; Ris: risankizumab; Ust: ustekinumab; Fil: filgotinib; Tof: tofacitinib; Upa: upadacitinib; Eta: etanercept; Inf: infliximab; Ada: adalimumab; Cer: certolizumab pegol; Gol: golimumab.