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. 2022 Jan 27;272(5):873–885. doi: 10.1007/s00406-022-01380-1

Table 1.

Demographics and clinical characteristics

Total sample, n = 293 Schizophrenia-spectrum, n = 123 Bipolar-spectrum, n = 170 Statistics p value
Mean (SD) Mean (SD) Mean (SD)
Age (years) 30.1 (9.9) 29.7 (8.9) 31 (10.5) t = − 1.092, df = 284 0.276
Female sex, n (%) 157 (53.0) 53 (43.1) 101 (59.4) X2 = 7.625, df = 2

0.006

BD > SZ

SFS interpersonal 223.4 (25.9) 217.1 (27.4) 227.9 (24.1) t = − 3.586, df = 291

0.000

BD > SZ

Duration of illness, yearsa 8.6 (9.0) 4.9 (6.6) 11.2 (9.5)

t = − 6.675,

df = 288

0.000

BD > SZ

IQ (WASI)b 108 (13.4) 104 (14.8) 110.9 (11.5)

t = − 4.277,

df = 204

0.000

BD > SZ

Total number of illness episodes 9.4 (16.2) 3.9 (4.8) 13.4 (19.9)

t = − 5.981,

df = 196

0.000

BD > SZ

Onset of illness ≤ 18 years, n (%) 123 (42.0) 25 (20.3) 98 (57.6)

X2 = 40.813,

df = 1

0.000

BD > SZ

Duration of untreated illness, weeksc 47 (145.3) 75 (173.3) 22 (109.5)

t = 2.764,

df = 226

0.008

SZ > BD

Premorbid social functioning (PAS)d 1.9 (2.3) 2.1 (2.4) 1.8 (2.3)

t = 1.196,

df = 286

0.233
Psychosis lifetime, n (%) 214 (72.1) 123 (100) 88 (52)

X2 = 82.386,

df = 1

0.000

SZ > BD

PANSS—total 47.8 (13.3) 55.4 (15.1) 42.3 (8.3)

t = 8.702,

df = 175

0.000

SZ > BD

PANSS—Positive 10.4 (3.9) 12.6 (4.4) 8.9 (2.5)

t = 8.488,

df = 178

0.000

SZ > BD

PANSS—Negative 11.2 (4.8) 14.0 (5.7) 9.2 (2.5)

t = 8.797,

df = 157

0.000

SZ > BD

Depression (PANSS item G6) 2.4 (1.3) 2.3 (1.2) 2.5 (1.4)

t = − 1.448,

df = 291

0.149
Anxiety (PANSS item G2) 2.8 (1.3) 2.7 (1.2) 3.1 (1.4)

t = − 1.688,

df = 291

0.092
YMRS—totale 2.6 (3.6) 2.7 (3.6) 2.5 (4.1)

t = .490,

df = 288

0.624
AUDITf 6.8 (6.0) 5.2 (4.9) 8.1 (6.5)

t = − 4.116,

df = 282

0.000

BD > SZ

DUDITg 3.2 (6.6) 3.2 (7.1) 3.2 (6.4)

t = − .068,

df = 281

0.946
ALS-SF—total 1.2 (0.71) 1.1 (0.65) 1.3 (0.73)

t = − 1.890,

df = 291

0.060
ALS-SF anxiety-depression 1.4 (0.87) 1.3 (0.83) 1.5 (0.90)

t = − 1.168,

df = 291

0.244
ALS-SF depression-elation 1.4 (0.74) 1.3 (0.71) 1.4 (0.76)

t = − 1.453,

df = 291

0.147
ALS-SF anger 0.80 (0.78) 0.67 (0.75) 0.90 (0.80)

t = − 2.559,

df = 291

0.011

SFS Social Functioning Scale, WASI Wechsler Abbreviated Scale of Intelligence, PAS Premorbid Adjustment Scale, PANSS Positive and Negative Syndrome Scale, YMRS Young Mania Rating Scale, AUDIT The Alcohol Use Disorders Identification Test, DUDIT Drug Use Disorders Identification Test, ALS-SF Affective Lability Scale Short Form

Statistically significant p values are in bold

a99% (n = 290) participants had data on duration of illness

b93% (n = 273) participants had data on IQ

c78% (n = 228) had data on duration of untreated illness

d98.2% (n = 288) participants had data on PAS

e99% (n = 290) participants had data on YMRS

f96.9% (n = 284) participants had data on AUDIT

g96.6% (n = 283) participants had data on DUDIT