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. 2022 Mar 11;61(5):2725–2735. doi: 10.1007/s00394-022-02846-7

Fig. 3.

Fig. 3

Serum M30 values and risk of liver fibrosis improve with weight loss during lifestyle intervention. A As a surrogate for NASH, patients were classified per M30 values with a cut-off set at 200U/L. Weight loss led to a decrease in participants with M30 values > 200U/L. ##p < 0.01, McNemar. B NFS was calculated and participants in whom liver fibrosis could be excluded are depicted in green, participants with indeterminate values are shown in yellow and those with definite fibrosis are shown in red. Weight loss during lifestyle intervention was associated with a marked decrease in the proportion of subjects at risk for liver fibrosis. **p < 0.01, Chi-squared test