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. 2022 Jul 13;12:11859. doi: 10.1038/s41598-022-15564-1

Table 1.

Patient characteristics. Comparison between the no hemorrhage and hemorrhage groups.

No hemorrhage
group (n = 35)
Hemorrhage
group (n = 16)
P value
Age (y)* 32 (22–42) 36.5 (26–48) 0.033
Past pregnancy (%)
 Yes 18 (51) 8 (50) 1.0**
 No 17 (49) 8 (50)
Preceding pregnancy (%)
 Method
    Ni 23 (66) 3 (19) 0.003**
    ART 12 (34) 13 (81)
    IVF-ET 11 13
    IUI 1 0
 Outcome
    SA 20 (57) 5 (31) 0.19**
    AA 5 (14) 4 (25)
    VD 10 (29) 6 (36)
    CS 0 (0) 1 (8)
 Trimester at delivery
    First 20 (57) 6 (38) 0.37**
    Second 6 (17) 3 (19)
    Third 9 (26) 7 (43)
 Intrauterine intervention§
    Yes 17 (49) 7 (43) 0.77**
    No 18 (51) 9 (57)
Findings at first visit
 Maximum diameter (mm)* 28 (6.9–68) 40 (17–71) 0.03
 PDCS (%)
    1 10 (29) 0 (0) 0.005**
    2 8 (22) 0 (0)
    3 7 (20) 7 (44)
    4 10 (29) 9 (56)
 βhCG (IU/L)* 9.2 (1.2–3,244.8) 50.6 (2.5–5,339.7) 0.007
 Hb (g/dL)* 11.7 (8.3–14.7) 9.6 (6.2–13.9) 0.005
Clinical course
 HR (%) 1 (3) 13 (81)
Length of follow-up (days)*
   Time from delivery (days) 40 (10–340) 34 (17–202)   0.77 
   To massive hemorrhage* 32.5 (6–74)
   To βHCG regression* 58 (26–146) 64.5 (16–91) 0.52
   To RPOC resolution* 103 (53–405) 75 (31–258) 0.29

Ni, natural intercourse; ART, assisted reproductive technology; IVF-ET, in vitro fertilization-embryo transfer; IUI, intrauterine insemination; SA, spontaneous abortion; AA, artificial abortion; VD, vaginal delivery; CS, cesarean section; PDCS, power Doppler color scoring; βhCG, serum β-human chorionic gonadotropin; Hb, serum hemoglobin; HR, hysteroscopic resection.

*median (range), pregnancy responsible for RPOC, §dilatation and curettage and manual removal of placenta, Mann–Whitney U Test, **Fisher exact test. Statistical significance was set at a P value of < 0.05.