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PS1 residues surrounding substrates P5 and P6 in the Aβ49-Aβ46-Aβ43-Aβ40-Aβ37 production line and their related FAD mutations
| Residues surrounding P5 | Residues surrounding P6 | |
|---|---|---|
| PS1 residues | S169, S170, L173, I213, L226, I229, M233, L286, I287, L383, I387 | M146, L150, I162, W165 |
| Related FAD mutations | S169P, ΔS169, S170F, L173W, I213L, I229F, M233T, M233L, L286V | M146L, L150P, W165G |
