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(a) Two-dimensional rendering of residues Y88 and Y89 in p27 taken from the centroid structure of two k-means clusters. (b) Distance between p27 residue Y89 and the center of mass of Cdk2 residues T14 and Y15. (c) The solvent-accessible surface area of Cdk2 T14 and Y15. (d) The solvent-accessible surface area of p27 Y89 when Cdk2 residues T14 and Y15 are phosphorylated to T2P14 and Y2P15. To see this figure in color, go online.
