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. 2022 Jul 13;13:4005. doi: 10.1038/s41467-022-30458-6

Fig. 2. Comparison of aRML and 263K prions.

Fig. 2

a Ribbon diagram of aRML core (stack of 5), with structural motifs as colored. b Overlay of aRML and 263K cores. c Contour EM density maps of aRML and 263K. Green arrows indicate peripheral unassigned densities associated with cationic residues in the N-terminal lobes of both strains, but absent in the aRML C-terminal lobe, consistent with aRML’s lack of glycans and glycolipid anchors. d Lateral views of aRML and 263K EM maps (stacks of 3) with stick models embedded in top rung. Arrowhead indicates protrusion of anvil-like head of the N β-arch. Underneath is a ribbon overlay of aRML and 263K monomers indicating differences in planarity.