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Drug sensitivity and cytotoxicity analysis in breast cancer cells. (A) Use of the database to query LSM1 gene signatures and screen for potential drugs. (B and C) Drug sensitivity of sgLSM1 gene to refametinib and trametinib in BRCA cell lines. (D and F) LSM1 efficacy of refametinib and trametinib in inhibiting breast cancer cells. (E and G) Drug sensitivity of different doses of refametinib and Trametinib in treating different breast cancer cells
