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. 2021 Sep 30;12(4):2057–2073. doi: 10.1016/j.apsb.2021.09.022

Figure 10.

Figure 10

TME remodeling by the liposomes. The intratumoral percentage of MDSCs (A), M2Φ cells (B), CD49b+ NK1.1+ cells (C), CD8+ granzyme B+ T cells (D) after treatment. (E) The reduced lactic acid production in the tumors after treatment. (F) Expression of CD206 and VEGF in the tumors after treatment. (G) Immunohistochemical staining (brown color) of iNOS, CD206, HDAC2, BRD4, PD-L1, CD31, and TGF-β1 in CT26 subcutaneous tumors (scale bar = 100 μm). Data are presented as mean ± SD (n = 3). ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.