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. 2021 Sep 30;12(4):2057–2073. doi: 10.1016/j.apsb.2021.09.022

Figure 2.

Figure 2

Macrophage regulation of Pano and JQ1. (A) Expression of CD206, HDAC2, PD-L1, iNOS, and p-STAT6 in M1Φ/M2Φ after treatment. (B) MΦ repolarization by Pano and JQ1 treatment. (C) Reduced BRD4 expression in M2Φ after treatment. (D) Illustration of the co-culture system of BMDMs and CT26 cells. (E) Statistical analysis of CD206+ F4/80+ MΦ after treatment. (F) Statistical analysis of PD-L1+ F4/80+ MΦ after treatment. Data are presented as mean ± SD (n = 3). ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.