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Major pathways of GDP-fucose biosynthesis and IgG Fc core fucosylation. FUK, Fucose Kinase; GDPP, GDP-fucose-pyrophosphorylase; GMD, GDP-mannose 4,6 dehydratase; FX, GDP-4-keto 6-deoxymannose 3,5-epimerase-4-reductase; FUT, Fucosyltransferase.
