Table 1.
Potential cut-off to predict raised intracranial pressure.
| Study | No of patients | Methods of evaluation | ONSD cut-off point | Sensitivity | Specificity |
|---|---|---|---|---|---|
| Kimberly et al. (13) | 15 | Linear ultrasoud probe (axial B-Scan) | 5 mm | 88% (95% CI: 47–99%) |
93% (95% CI: 78–99%) |
| Adauayi et al. (14) | 160 (80 controls) | Linear ultrasoud probe (axial B-Scan) | 5.2 mm | 81.2% (95% CI: 69.9–89.6%) |
100% (95% CI: 71.5–100%) |
| Lee et al. (15) | 134 | Linear ultrasoud probe (transverse B-Scan) | 5.5 mm (in Korean population) | 99% (95% CI: 93–100%) |
85% (95% CI: 66–95%) |
| Bolesch et al. (16) | 45 | Linear ultrasoud probe (transvere B-Scan) | 5.7 mm | 53.5% | 100.0% |
| Salahuddin et al. (17) | 102 | Linear ultrasoud probe (transverse B-Scan) | 5.7 mm (non-traumatic cerebral edema) | 84% (95% CI: 70–87%) |
71% (95% CI: 70–87%) |
| Wang et al. (18) | 279 | Linear ultrasoud probe (transverse and sagittal B-Scan) | 4.1 mm (in Chinese population) | 95% | 92% |
| Komut et al. (19) | 100 | Linear ultrasoud probe (transverse and sagittal B-Scan) | 4.7 mm | 70% | 86% |
| Moretti et al. (20) | 63 | Linear ultrasoud probe (transverse and sagittal B-Scan) | 5.2 mm (in intracranial hemorrhages) | 93% (95% CI: 77.2–99%) |
74% (95% CI: 61.5–84%) |
| Moretti et al. (21) | 53 | Linear ultrasoud probe (transverse and sagittal B-Scan) | 5.2 mm (in intracranial hemorrhages) | 94% (95% CI: 88–100%) |
76% (95% CI: 65–87%) |
| Major et al. (22) | 26 | Linear ultrasoud probe (B-Scan, with no specified plane) | Not detected | 86% (95% CI: 42–99%) |
100% (95% CI: 79–100%) |
ONSD, Optic nerve sheath diameter. 95% CI: 95% Confidence intervals.