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. 2021 Dec 29;12(4):2029–2042. doi: 10.1016/j.apsb.2021.12.015

Figure 9.

Figure 9

Study of biocompatibility. (A) Cell viability of Caco-2 and E12 cells after incubation with EXOs. Error bars represent SD (n = 3). (B) LDH release from Caco-2 cells after incubation with EXOs. Positive control: 1% Triton solution. Error bars represent SD (n = 3). (C) Hemolysis efficiency of RBCs after incubation with EXOs. Positive control: 1% Triton solution. Error bars represent SD (n = 3). (D) The body weight of ICR mice during the administration of EXOs or saline. Error bars represent SD (n = 4). (E, F) Levels of ALT, ALP, AST, ALB and TP after 7 consecutive days of oral administration of EXOs (2 mg/kg) or saline. Error bars represent SD (n = 3).