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. 2021 Oct 22;12(4):2103–2119. doi: 10.1016/j.apsb.2021.10.010

Figure 7.

Figure 7

Intratumoral activation of immune response and immunologic mechanisms. (A) FCM examination of tumor-infiltrating CD8+ and CD4+ T cells of tumors from mice with different treatments (Gated by CD3+ T cells). (B) FCM examination of tumor-infiltrating Tregs (CD4+CD25+Foxp3+) of tumors from mice with different treatments (Gated by CD4+ T cells). (C) FCM examination of IFN-γ+CD8+ T cells (Gated by CD3+ T cells). (D) Proportion of CD4+ and CD8+ T cells according to (A). (E) Proportion of Tregs according to (B). (F) Proportion of IFN-γ+CD8+ T cells according to (C). All error bars present as mean ± SD (n = 3). ∗∗∗P < 0.001.