Table 3.
Risk of cancer occurred for people with and without HPV infection.
| HPV | Non–HPV | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| PM | Event | Incidence rate† | PM | Event | Incidence rate† | Crude HR | Adjusted HR | |||
| Head and Neck Cancer | 44,357,317 | 808 | 21.86 (20.40–23.42) | 89,136,676 | 1,064 | 14.32 (13.49–15.21) | 1.527(1.393–1.673)* | 1.595(1.453–1.749)* | ||
| Cervical Cancer | 22,388,511 | 777 | 41.65 (38.82–44.68) | 45,020,697 | 712 | 18.98 (17.63–20.42) | 2.195(1.983–2.430)* | 2.225(2.008–2.464)* | ||
| Lung Cancer–All | 44,357,317 | 1,458 | 39.44 (37.47–41.52) | 89,136,676 | 1,897 | 25.54 (24.41–26.71) | 1.546(1.444–1.655)* | 1.539(1.436–1.649)* | ||
| Male | 21,968,806 | 869 | 47.47(44.41–50.73) | 44,115,979 | 1,228 | 33.40(31.59–35.32) | 1.422(1.304–1.551)* | 1.434(1.312–1.566)* | ||
| Female | 22,388,511 | 589 | 31.57(29.12–34.23) | 45,020,697 | 669 | 17.83(16.53–19.24) | 1.772(1.586–1.980)* | 1.742(1.557–1.948)* | ||
| Age <60 years | 39,453,993 | 519 | 15.79(14.48–17.20) | 79,157,462 | 611 | 9.26(8.56–10.03) | 1.705(1.517–1.917)* | 1.664(1.478–1.873)* | ||
| Age ≥60 years | 4,903,324 | 939 | 229.81(215.57–244.98) | 9,979,214 | 1,286 | 154.64(146.42–163.33) | 1.491(1.371–1.622)* | 1.483(1.361–1.616)* | ||
| Squamous Cell Carcinoma | 44,357,317 | 167 | 4.52(3.88–5.26) | 89,136,676 | 326 | 4.39(3.94–4.89) | 1.030(0.855–1.241) | 1.092(0.903–1.320) | ||
| Male | 21,968,806 | 138 | 7.54 (6.38–8.91) | 44,115,979 | 289 | 7.86 (7.01–8.82) | 0.960(0.784–1.175) | 0.949(0.773–1.164) | ||
| Female | 22,388,511 | 29 | 1.55 (1.08–2.24) | 45,020,697 | 37 | 0.99 (0.71–1.36) | 1.576(0.969–2.563) | 1.540(0.945–2.509) | ||
| Age <60 years | 39,453,993 | 36 | 1.09 (0.79–1.52) | 79,157,462 | 62 | 0.94 (0.73–1.21) | 1.165(0.773–1.757) | 1.151(0.762–1.739) | ||
| Age ≥60 years | 4,903,324 | 131 | 32.06 (27.01–38.05) | 9,979,214 | 264 | 31.74 (28.14–35.82) | 1.013(0.822–1.249) | 0.984(0.796–1.215) | ||
| Adenocarcinoma | 44,357,317 | 981 | 26.54(24.93–28.25) | 89,136,676 | 1,119 | 15.06(14.21–15.97) | 1.763(1.618–1.921)* | 1.714(1.572–1.870)* | ||
| Male | 21,968,806 | 489 | 26.71 (24.44–29.19) | 44,115,979 | 581 | 15.80 (14.57–17.14) | 1.691(1.500–1.908)* | 1.646(1.458–1.858)* | ||
| Female | 22,388,511 | 492 | 26.37 (24.14–28.81) | 45,020,697 | 538 | 14.34 (13.18–15.60) | 1.841(1.629–2.080)* | 1.812(1.603–2.049)* | ||
| Age <60 years | 39,453,993 | 415 | 12.62 (11.46–13.90) | 79,157,462 | 441 | 6.69 (6.09–7.34) | 1.889(1.652–2.160)* | 1.847(1.614–2.112)* | ||
| Age ≥60 years | 4,903,324 | 566 | 138.52 (127.57–150.42) | 9,979,214 | 678 | 81.53 (75.62–87.90) | 1.705(1.525–1.907)* | 1.653(1.477–1.850)* | ||
PM, person–months.
*
statistic significance with p < 0.05.
†
crude incidence rate, per 100,000 person–years.