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. 2022 Jun 30;9:937561. doi: 10.3389/fmed.2022.937561

Table 3.

Uncontrolled trials of RTX in SSc-ILD.

References No of patients Disease RTX scheme Follow up Outcomes Safety of RTX
Lafyatis et al. (25) 15 SSc RA scheme 6 m Stable PFTs and HRCT score No serious AE
Daoussis et al. (26) 8 SSc Lymphoma scheme 2 y Improved PFTs and HRCT score 3 serious infections, 2 infusion reactions
Smith et al. (27) 8 SSc RA scheme 2 y Increased FVC, stable DLCO 5 serious AE/1 death
Bosello et al. (28) 20 SSc RA scheme 2 y Stable PFTs and HRCT score 4 serious AE
Fraticelli et al. (29) 15 SSc RA scheme 6 m Improved FVC, stable DLCO, Imroved HRCT No serious AE
Vilela et al. (30) 10 SSc RA scheme 6 m Stable PFTs
Sari et al. (31) 15 SSc Ra scheme Variable Stable PFTs No serious AE