Table 3.

Accuracy of CLE for the detection of wheat sensitivity and for any food sensitivity after 2, 6 and 12 months

Time point	Accuracy of CLE
	For wheat sensitivity				For any food sensitivity
	2 months		6 months	12 months	6 months	12 months
	Blinded CLE evaluation	CLE evaluation by examiner
Sensitivity (97.5% CI)	51.4% (38.7% to 63.9%)	50% (37.4% to 62.6%)	72.2% (53.6% to 85.4%)	70% (52.3% to 83.2%)	83.1% (69.6% to 91.3%)	82.1% (69.5% to 90.2%)
Specificity (97.5% CI)	67.9% (52.9% to 79.9%)	69.6% (54.7% to 81.3%)	40% (20% to 64%)	36.8% (17.4% to 61.8%)	32% (15.7% to 54.3%)	33.3% (15.6% to 57.5%)
Positive predictive value (95% CI)	67.9% (54.8% to 78.6%)	68.5% (55.3% to 79.3%)	68.4% (52.5% to 80.9%)	70% (54.6% to 81.9%)	74.2% (62.6% to 83.3%)	79.7% (68.8% to 87.5%)
Negative predictive value (95% CI)	51.4% (40.2% to 62.4%)	51.3% (40.3% to 62.2%)	44.4% (24.6% to 66.3%)	36.8% (19.1% to 59%)	44.4% (24.6% to 66.3%)	36.8% (19.1% to 59%)
Positive likelihood ratio (95% CI)	1.6 (1.03 to 2.48)	1.65 (1.04 to 2.6)	1.2 (0.8 to 1.82)	1.11 (0.74 to 1.65)	1.22 (0.91 to 1.64)	1.23 (0.89 to 1.7)
Negative likelihood ratio (95% CI)	0.72 (0.53 to 0.96)	0.72 (0.54 to 0.96)	0.69 (0.33 to 1.47)	0.81 (0.38 to 1.73)	0.53 (0.24 to 1.18)	0.54 (0.24 to 1.19)

CLE, confocal laser endomicroscopy.;.