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. 2022 Jun 21;32(7):830–845. doi: 10.1136/ijgc-2021-003262

Figure 6.

Figure 6

Differentiated vulvar intraepithelial neoplasia (dVIN). The histologic changes of dVIN are very subtle, and may be missed. Here there is basal atypia and acanthosis, but overall maturation is maintained. P53 and Ki-67 showed increased basal activity, and p16 was not block-positive, not shown (hematoxylin and eosin, x 20 magnification)