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. 2022 Jun 30;12:922422. doi: 10.3389/fcimb.2022.922422

Table 3.

Comparison of cytokine levels in relation to epidemiological variables among patients with acute COVID-19.

Variables IL-17 (pg/mL) Median (IIQ) IFN-γ (pg/mL) Median (IIQ) TNF-α (pg/mL) Median (IIQ) IL-10 (pg/mL) Median (IIQ) IL-6 (pg/mL) Median (IIQ) IL-4 (pg/mL) Median (IIQ) IL-2 (pg/mL) Median (IIQ)
Sex*
 Female 15.44 (17.66) 8.21 (3.71) 6.00 (3.50) 8.96 (3.82) 12.56 (8.84) 9.43 (7.02) 6.76 (2.03)
 Male 15.45 (11.58) 8.24 (3.67) 6.25 (3.28) 9.95 (3.25) 11.70 (7.90) 8.09 (4.75) 6.96 (1.80)
 p 0.9735 0.7270 0.7688 0.1618 0.8733 0.2121 0.3360
Age (years)**
 21-40 15.80 (9.30) 8.37 (3.09) 7.67 (3.94) 8.56 (2.32) 11.39 (4.27) 10.34 (4.82) 7.44 (2.10)
 41-60 15.31 (16.76) 8.35 (3.29) 6.78 (2.94) 9.59 (3.50) 12.71 (9.24) 8.46 (5.26) 6.88 (1.95)
 >60 11.74 (16.76) 8.05 (3.05) 5.95 (3.14) 10.43 (2.80) 14.51 (11.97) 7.86 (5.17) 5.52 (1.77)
 p 0.6310 0.9853 0.0257 0.1674 0.0636 0.2700 0.1263
Comorbidities *
 Yes 16.40 (17.03) 7.70 (2.87) 5.69 (2.33) 9.63 (4.67) 13.13 (11.68) 7.27 (4.88) 6.61 (1.73)
 No 15.45 (9.30) 8.65 (3.02) 7.05 (3.59) 9.39 (3.08) 11.35 (4.96) 10.19 (4.84) 7.49 (1.68)
 p 0.9922 0.2527 0.0030 0.9893 0.0891 0.0020 0.0021

IIQ, interquartile range; * Mann–Whitney test; ** Kruskal–Wallis test.