TABLE 1.

Correlation between CD9 expression in tumor/stroma and clinicopathologic characteristics of PDAC patients in the non‐neoadjuvant and neoadjuvant group

	Non‐neoadjuvant group (n = 211)						Neoadjuvant group ‐ Fudan cohort (n = 98)						Neoadjuvant group ‐ validation cohort (n = 81)
	CD9 expression in tumor		p	CD9 expression in stroma		p	CD9 expression in tumor		p	CD9 expression in stroma		p	CD9 expression in tumor		p	CD9 expression in stroma		p
	Low	High		Negative	Positive		Low	High		Negative	Positive		Low	High		Negative	Positive
Age			0.736			0.398			0.535			0.667			0.311			0.565
<Median	64	41		75	30		21	25		25	21		24	16		24	16
≥Median	67	39		70	36		27	25		26	26		20	21		22	19
Gender			0.638			0.295			0.310			0.222			0.232			0.704
Male	78	45		88	35		27	23		23	27		24	25		27	22
Female	53	35		57	31		21	27		28	20		20	12		19	13
Tumor location			0.365			0.217			0.563			0.940			0.965			0.175
Head&neck	69	37		77	29		21	19		21	19		20	17		18	19
Body&tail	62	43		68	37		27	31		30	28		24	20		28	16
Tumor differentiation			0.229			0.092			0.012			0.903			0.007			0.855
Well to moderate	75	39		84	30		35	24		31	28		33	17		28	22
Poor	56	41		61	36		13	26		20	19		11	20		18	13
Vascular invasion			0.291			0.633			0.098			0.140			0.032			0.236
No	88	48		95	41		31	24		25	30		32	20		27	25
Yes	43	32		50	25		17	26		26	17		12	17		19	10
Perineural invasion			0.143			0.609			0.269			0.480			0.243			0.697
No	32	27		39	20		12	8		9	11		16	9		15	10
Yes	99	53		106	46		36	42		42	36		28	28		31	25
Tumor size stage			0.147			0.740			0.281			0.057			0.590			0.037
1	38	16		35	19		16	10		13	13		9	10		6	13
2	59	34		66	27		22	25		20	27		24	16		25	15
3	34	30		44	20		10	15		18	7		11	11		15	7
Lymph node stage			0.807			0.834			0.051			0.143			0.033			0.070
0	55	31		58	28		28	17		19	26		29	15		20	24
1	52	31		59	24		15	26		26	15		13	15		19	9
2	24	18		28	14		5	7		6	6		2	7		7	2
TNM stage			0.687			0.602			0.044			0.021			0.046			0.028
I	47	25		47	25		22	11		11	22		21	10		12	19
II	60	37		70	27		21	32		34	19		21	20		27	14
III	24	18		28	14		5	7		6	6		2	7		7	2