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. 2022 Jun 30;10:907104. doi: 10.3389/fbioe.2022.907104

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Copyright © 2022 Deng, Cui, Shi, Zhu, Wang, Shao and Qin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcriptome analysis of placental trophoblast-like tissues under static and dynamic conditions. (A) Hierarchical clustering heatmap of upregulated DEGs in the flow group compared with the static group, the undifferentiated hiPSC group. (B–D) GO enrichment of upregulated DEGs according to the (B) cellular component, (C) molecular function, and (D) biological process. (E) KEGG analysis of upregulated DEGs in 3D tissues under dynamic conditions compared with static conditions.