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. 2022 Jun 30;13:927277. doi: 10.3389/fmicb.2022.927277

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Copyright © 2022 Bi, Cui, Yao, Chang, Wang, Zhang, Xu, Zhuang and Hua.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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B. longum alleviates DSS-induced acute inflammatory bowel disease in mice. (A) Percentage change in body weight. (B) Disease activity index score, a composite measure of weight loss, stool consistency, and blood in stool. (C) Representative photographs showing colon tissue. (D) Changes in colon length. (E) Representative hematoxylin and eosin-stained sections of colon. (F) Histopathological scores. Data are represented as mean ± SD of three independent experiments (n = 8). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, and ns: not significant.