Table 4.

Top 5 Open Target associated disease phenotypes for the 3 genes that were found common in all Enrichr-GO annotation terms (JAK3, ZEB2, and PLCG2).

Gene	name	Overall Association Score	Genetic Associations	Somatic Mutations	drugs	Pathways Systems Biology	textMining	Rna Expression	Animal Models
JAK3	T-B + severe combined immunodeficiency due to JAK3 deficiency	0.79354891	0.86210536	No data	No data	No data	No data	No data	0.639792477
	Rheumatoid arthritis	0.60889198	No data	No data	0.978608	No data	0.459466938	No data	No data
	Ulcerative colitis	0.58868596	No data	0.455948098	0.845344	No data	0.094824248	0.105747791	0.311929292
	Ankylosing spondylitis	0.47300062	No data	No data	0.777442	No data	0.012158616	No data	No data
	Immune system disease	0.4638375	No data	No data	0.759913	No data	0.061279424	No data	No data
ZEB2	Coronary artery disease	0.37565129	0.61093509	No data	No data	No data	0.139655214	No data	No data
	Migraine disorder	0.32028527	0.52684495	No data	No data	No data	No data	No data	No data
	Crohn's disease	0.28942152	0.47607643	No data	No data	No data	No data	No data	No data
	Inflammatory bowel disease	0.27025168	0.4427197	No data	No data	No data	0.036475848	No data	No data
	Acute myeloid leukemia	0.25080082	No data	No data	No data	0.371977657	0.811412861	No data	No data
PLCG2	PLCG2-associated antibody deficiency and immune dysregulation	0.69828022	0.78440264	No data	No data	No data	0.100353358	No data	No data
	NLRP12-associated hereditary periodic fever syndrome	0.56458052	0.68230439	No data	No data	No data	No data	No data	No data
	Venous thromboembolism	0.4358949	0.71701402	No data	No data	No data	No data	No data	No data
	Coronary artery disease	0.4320773	0.71073435	No data	No data	No data	No data	No data	No data
	Inflammatory bowel disease	0.40521025	0.6638044	No data	No data	No data	0.054713772	No data	No data