TABLE 3.
Comparison | miRNA | AUC | Sensitivity | Specificity | p-value |
---|---|---|---|---|---|
NT x BC | miR-142-5p | 0.7532 | 65.86 | 76.00 | <0.0001 |
miR-150-5p + miR-142-5p panel | 0.9317 | 88.76 | 86.67 | <0.0001 | |
miR-142-5p + miR-320a-3p panel | 0.7681 | 52.07 | 89.33 | <0.0001 | |
miRNAs complete panel* | 0.9345 | 87.68 | 90.67 | < 0.0001 | |
NT x LA | miR-142-5p | 0.7371 | 62.40 | 76.00 | <0.0001 |
miR-150-5p + miR-320a-3p panel | 0.7458 | 69.60 | 70.67 | <0.0001 | |
miR-150-5p + miR-142-5p panel | 0.9179 | 84.80 | 86.67 | <0.0001 | |
miR-142-5p + miR-320a-3p panel | 0.7738 | 72.00 | 72.00 | <0.0001 | |
miRNAs complete panel* | 0.9266 | 85.20 | 90.67 | < 0.0001 | |
NT x BLBC | miR-142-5p | 0.8671 | 72.29 | 93.33 | <0.0001 |
miR-150-5p + miR-142-5p panel | 0.9680 | 93.90 | 92.00 | <0.0001 | |
miR-142-5p + miR-320a-3p panel | 0.8694 | 70.73 | 92.00 | <0.0001 | |
miRNAs complete panel* | 0.9689 | 93.90 | 92.00 | < 0.0001 | |
LA x BLBC | miR-142-5p | 0.7220 | 72.29 | 67.60 | <0.0001 |
miR-150-5p + miR-142-5p panel | 0.7711 | 68.67 | 78.80 | <0.0001 | |
miR-142-5p + miR-320a-3p panel | 0.7274 | 59.04 | 80.80 | <0.0001 | |
miRNAs complete panel* | 0.7728 | 63.86 | 80.80 | < 0.0001 |
Only AUC>0.7 is presented. In bold and underlined are the highest AUC values for the group comparison. (*): the four miRNAs were evaluated together. Sensitivity and specificity are presented as percentage (%). BC, breast cancer; NT, non-tumor tissue; LA, luminal A; and BLBC, basal-like breast cancer.