Skip to main content
. 2022 Jun 30;13:865472. doi: 10.3389/fgene.2022.865472

TABLE 3.

Data about receiver operating characteristic (ROC) curves to investigate the diagnostic potential of miRNAs on TCGA samples.

Comparison miRNA AUC Sensitivity Specificity p-value
NT x BC miR-142-5p 0.7532 65.86 76.00 <0.0001
miR-150-5p + miR-142-5p panel 0.9317 88.76 86.67 <0.0001
miR-142-5p + miR-320a-3p panel 0.7681 52.07 89.33 <0.0001
miRNAs complete panel* 0.9345 87.68 90.67 < 0.0001
NT x LA miR-142-5p 0.7371 62.40 76.00 <0.0001
miR-150-5p + miR-320a-3p panel 0.7458 69.60 70.67 <0.0001
miR-150-5p + miR-142-5p panel 0.9179 84.80 86.67 <0.0001
miR-142-5p + miR-320a-3p panel 0.7738 72.00 72.00 <0.0001
miRNAs complete panel* 0.9266 85.20 90.67 < 0.0001
NT x BLBC miR-142-5p 0.8671 72.29 93.33 <0.0001
miR-150-5p + miR-142-5p panel 0.9680 93.90 92.00 <0.0001
miR-142-5p + miR-320a-3p panel 0.8694 70.73 92.00 <0.0001
miRNAs complete panel* 0.9689 93.90 92.00 < 0.0001
LA x BLBC miR-142-5p 0.7220 72.29 67.60 <0.0001
miR-150-5p + miR-142-5p panel 0.7711 68.67 78.80 <0.0001
miR-142-5p + miR-320a-3p panel 0.7274 59.04 80.80 <0.0001
miRNAs complete panel* 0.7728 63.86 80.80 < 0.0001

Only AUC>0.7 is presented. In bold and underlined are the highest AUC values for the group comparison. (*): the four miRNAs were evaluated together. Sensitivity and specificity are presented as percentage (%). BC, breast cancer; NT, non-tumor tissue; LA, luminal A; and BLBC, basal-like breast cancer.