TABLE 1.
ADME core gene panel.
| Gen | Transcript (NCBI) | Class |
|---|---|---|
| ABCB1 | NM_001348946.2 | Transporter |
| ABCC2 | NM_000392.5 | Transporter |
| ABCG2 | NM_000392.5 | Transporter |
| CYP1A1 | NM_001319217.2 | Phase I |
| CYP1A2 | NM_000761.5 | Phase I |
| CYP2A6 | NM_000762.6 | Phase I |
| CYP2B6 | NM_000767.5 | Phase I |
| CYP2C19 | NM_000769.4 | Phase I |
| CYP2C8 | NM_000770.3 | Phase I |
| CYP2C9 | NM_000771.4 | Phase I |
| CYP2D6 | NM_000106.6 | Phase I |
| CYP2E1 | NM_000773.4 | Phase I |
| CYP3A4 | NM_017460.6 | Phase I |
| CYP3A5 | NM_000777.5 | Phase I |
| DPYD | NM_000110.4 | Phase I |
| DRD2 | NM_000795.4 | Pharmacodynamic |
| GSTM1 | NM_000561.4 | Phase II |
| GSTP1 | NM_000852.4 | Phase II |
| GSTT1 | NM_000853.3 | Phase II |
| NAT1 | NM_000662.8 | Phase II |
| NAT2 | NM_000015.3 | Phase II |
| SLC15A2 | NM_021082.4 | Transporter |
| SLC22A1 | NM_003057.3 | Transporter |
| SLC22A2 | NM_003058.4 | Transporter |
| SLC22A6 | NM_153276.3 | Transporter |
| SLCO1B1 | NM_006446.5 | Transporter |
| SLCO1B3 | NM_019844.4 | Transporter |
| SULT1A1 | NM_001055.3 | Phase II |
| TPMT | NM_000367.4 | Phase II |
| UGT1A1 | NM_000463.3 | Phase II |
| UGT1A9 | NM_019076.4 | Phase II |
| UGT2B15 | NM_001076.4 | Phase II |
| UGT2B17 | NM_001077.3 | Phase II |
| UGT2B7 | NM_001074.4 | Phase II |
| VKORC1 | NM_024006.6 | Pharmacodynamic |