Table 4.
Open field test activity in different extracts of the VM seeds.
| Groups | Dose (p. o.) (mg/kg) |
Number of movements |
|||
|---|---|---|---|---|---|
| 0 min | 30 min | 60 min | 90 min | ||
| Control | 0.5 mL/mice | 278.33 ± 0.33 | 284 ± 0.58 | 290 ± 4.20 | 298.56 ± 5.60 |
| Diazepam | 1 | 130.45 ± 5.62 | 125.65 ± 1.23*** | 119.68 ± 3.45*** | 115.56 ± 4.21*** |
| MESVM | 200 | 270.33 ± 0.88 | 281 ± 0.58 | 285 ± 0.00 | 294.67 ± 2.91 |
| MESVM | 400 | 275 ± 0.00 | 283 ± 1.15 | 287 ± 0.58 | 296 ± 3.06 |
| CFFSVM | 400 | 277.67 ± 1.45 | 280.33 ± 0.88 | 289 ± 1.53 | 295.7 ± 0.67 |
| HFSVM | 400 | 278.7 ± 0.67 | 283.56 ± 1.76 | 289 ± 0.58 | 296.33 ± 1.86 |
| CTCFSVM | 400 | 275 ± 2.65 | 282.67 ± 1.86 | 286 ± 0.58 | 293.67 ± 1.45 |
| AESVM | 400 | 277 ± 0.58 | 284 ± 1.15 | 288.33 ± 3.84 | 296.67 ± 0.33 |
Values are shown as means of five replicates (n = 5) ± SEM. *** and ** indicate statistically high significance (P < 0.001) and moderate significance (P < 0.01), respectively comparing with the negative control.