Fig. 2.

Anti-inflammatory effect of topical application of essential oils mix of sweet orange peel, cumin, and allspice on ear edema induced by croton oil in Balb-c mice. Essential oils mix was tested at 100, 500, and 1,000 mg/kg body weight; indomethacin was used as a positive control at 10 mg/kg body weight, while no treatment was applied to the negative control. Values are represented as mean ± SE. ∗∗∗∗p < 0.001 compared to negative control. A statistically significant difference was not found = n.s.