Table 7.

Highly Prevalent Pathogens in Patients Suffering Multiple Infections

	OR	95% CI	P	Incidence Rate Group 1	Incidence Rate Group 2
Candida non-albicans spp.	23.70	[3.00–187.09]	.003	7.3 (10/137)	0.7 (2/302)
Candida albicans	19.86	[4.50–87.57]	<.001	11.7 (16/137)	0.7 (2/302)
EBV	9.05	[1.02–81.77]	.035	2.9 (4/137)	0.3 (1/302)
Pneumocystis jirovecii	5.68	[1.09–29.66]	.033	3.6 (5/137)	0.7 (2/302)
Klebsiella spp.	5.44	[5.44–9.59]	<.001	29.9 (41/137)	7.3 (22/302)
Pseudomonas aerguinosa	4.27	[2.71–8.40]	<.001	18.2 (25/137)	5.0 (15/302)
Enterococcus spp.	4.60	[2.94–7.21]	<.001	48.9 (67/137)	17.2 (52/302)
Staph. coag. negative	2.98	[1.62–5.48]	<.001	19.0 (26/137)	7.3 (22/302)
Enterobacter	2.80	[1.18–6.66]	.015	8.8 (12/137)	3.3 (10/302)
E. coli	2.64	[1.67–4.16]	<.001	36.5 (50/137)	17.8 (54/302)
CMV	1.80	[1.13–2.86]	.013	29.9 (41/137)	19.2 (58/302)

First-year pathogen incidence rates in patients suffering >2 infections/year (n = 137) were compared with those in patients suffering 1 or 2 infections/year (n = 302). Not significant: BK virus (P = .065), Streptococcus spp. (P = .090), Staphylococcus aureus (P = .140), herpes simplex virus–1 (P = .277), influenza A (P = .277), norovirus (P = .277), respiratory syncytial virus (P = .277), herpes simplex virus–2 (P = .297), Clostridium difficile (P = .314), varicella zoster virus (P = 0.393), Aspergillus fumigatus (P = .497).

Abbreviations: CMV, cytomegalovirus; EBV, Epstein-Barr virus; OR, odds ratio; Staph. coag. negative, Staphylococcus coagulase negative.