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The cytotoxic effect of selected compounds 3a, 3f, and 3t on the SH-SY5Y cell line.
| Compound | n | R | R′ | SH-SY5Y cell viability (% of control) a |
|---|---|---|---|---|
| 1 µM | ||||
| 3a | 3 | H | H | 81.2 ± 10.0 |
| 3f | 3 | 6-NO2 | H | 83.6 ± 3.4 |
| 3t | 3 | 6-NO2 | H | 84.8 ± 6.8 |
Cell viability is expressed as the mean percentage of viable cells compared with the untreated cells using the MTT assay protocol. The data are the mean ± SEM.
