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. 2022 Jul 13;5(7):e2221616. doi: 10.1001/jamanetworkopen.2022.21616

Table 1. Serologic Data of 769 Serum Samples Obtained From 659 Individuals With Confirmed COVID-19 Among Different Age Classes, Overall and Stratified by Time From Baselinea.

Variable Anti-RBD, median (IQR), kBAU/L
All data 1-4 mo from onset 5-9 mo from onset >10 mo from onset
Age class, y
<3 304.83 (139.0-519.6) 342.8 (179.5-519.6) 284.3 (162.5-519.6) 146.2 (62.8-231.2)
≤3 169.3 (103.1-277.1) 234.6 (113.5-347.9) 118.2 (70.6-192.5) 115.6 (45.9-160.6)
≤6 126.2 (74.0-207.8) 164.1 (79.1-236) 119.7 (77.4-165.2) 90.6 (62.4-111.8)
≤12-18 98.2 (44.7-169.0) 103.1 (46.3-170.2) 89.6 (45.9-170.2) 48.6 (18.1-95.7)
≥18 55.6 (24.2-136.0) 64.5 (26.2-140.9) 49.8 (22.5-114.7) 36.7 (13.5-108.5)
P valueb <.001 <.001 <.001 .02

Abbreviations: kBAU/L, kilo–binding antibody units per liter; RBD, receptor-binding domain.

a

Serum samples at the last time point for 17 people whose last S-RBD IgG titer was higher than the previous one were excluded from the analysis.

b

Kruskal-Wallis test.