Table 2. Participant-Paired Serologic Data of 56 Patients Who Were Sampled at Least Twicea.
| Age class, y | Time from baseline, mean (SD), d | Anti-RBD | |
|---|---|---|---|
| Median (IQR) kBAU/L | P valueb | ||
| First analysis | |||
| <6 | |||
| First (1-4 mo) | 98.0 (33.3) | 455.1 (238.9-519.6) | .06 |
| Intermediate (5-9 mo) | 205.0 (31.7) | 190.6 (113-519.6) | |
| 6-18 | |||
| First (1-4 mo) | 83.9 (28.6) | 220.4 (155.9-519.6) | .004 |
| Intermediate (5-9 mo) | 195 (33.9) | 106.1 (68.0-158.9) | |
| ≥18 | |||
| First (1-4 mo) | 87.2 (26.2) | 104.8 (69.7-138.1) | <.001 |
| Intermediate (5-9 mo) | 198.8 (28.6) | 52.0 (27.7-56.7) | |
| Second analysis | |||
| <6 | |||
| First (1-4 mo) | 80 (30.4) | 475.6 (308.0-519.6) | .002 |
| Late (≥10 mo) | 360 (26) | 132.7 (107-231.2) | |
| 6-18 | |||
| First (1-4 mo) | 82.9 (25) | 180.3 (76.6-372.4) | <.001 |
| Late (≥10 mo) | 392.4 (53.3) | 71.4 (29.9-113.7) | |
| ≥18 | |||
| First (1-4 mo) | 82.1 (24.8) | 121.2 (68.4-209.6) | <.001 |
| Late (≥10 mo) | 380.9 (51.2) | 48.1 (19.9-80.5) | |
Abbreviations: kBAU/L, kilo–binding antibody units per liter; RBD, the receptor binding domain.
a
Overall, 31 patients were evaluated 1 to 4 months (mean [SD], 89.2 [38.6] days) and 5 to 9 months (mean [SD], 199.2 [30.3] days) from baseline, and 40 patients were evaluated 1 to 4 months (mean [SD], 81.9 [25.7] days) and 10 or more months (mean [SD], 380.0 [47.4] days) from baseline.
b
Wilcoxon signed-rank test.