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. 2022 Jun 9;11(3):CNS89. doi: 10.2217/cns-2022-0009

Table 1. . Patient and tumor characteristics (n = 196).

Age at diagnosis (years)
Median 9  
Range 1 to 18  
IQR 5 to 13  
Sex Number of patients Percentage
Male 126 64.3
Female 70 35.7
Comorbidities and other illnesses 14 7.1
Respiratory 7 3.6
Autism spectrum disorder 2 1
Attention deficit hyperactivity disorder 1 0.5
Ventricular septal defect 1 0.5
G6PD deficiency 1 0.5
Polycythemia vera 1 0.5
Cellulitis 1 0.5
Tumor-related syndromes 10 5.1
Tuberous sclerosis complex 5 2.6
Neurofibromatosis type II 4 2
Neurofibromatosis type I 1 0.5
Income cluster
Poor 32 16.3
Low to lower middle income 112 57.1
Middle to upper middle income 47 24
Mother's highest educational attainment
Elementary 12 6.1
High school/vocational 87 44.4
College/post-graduate 56 28.6
Father's highest educational attainment
Elementary 14 7.1
High school/vocational 78 39.8
College/post-graduate 53 27
Tumor size (volume)
Median 35.2 cm3  
Range 1.5 to 611 cm3  
IQR 18.6 to 60 cm3  
Tumor location Number of patients Percentage
Supratentorial 98 50
  Cerebrum 36 18.4
  Sellar-suprasellar 31 15.8
  Pineal 31 15.8
Infratentorial 98 50
  Posterior fossa 82 41.8
  Brainstem 16 8.2
Tumor grade
WHO grade I 59 30.1
WHO grade II 12 6.1
WHO grade III 1 0.5
WHO grade IV 74 37.8
Histopathology
Medulloblastoma 43 21.9
Low grade glioma 40 20.4
High grade glioma 37 18.9
Germ cell tumors 24 12.2
Craniopharyngioma 14 7.1
Ependymoma 10 5.1
Schwannoma 6 3.1
Pituitary adenoma 3 1.5
ATRT 2 1
Metastasis at diagnosis 3 1.5

ATRT: Atypical teratoid rhabdoid tumor; IQR: Interquartile range.