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. 2022 Jun 30;9:828414. doi: 10.3389/fmed.2022.828414

Table 3.

Shows the changes primary and secondary outcomes in fatigue, sleep, anxiety and depression scores measured by MFI-20, PSQI, and HADS scales from T0 to T1.

CBT (n = 44) PLWNT (n = 45) PLWNT vs. CBT
T0 T1 Within T0 T1 Within Between
(X ±S) (X ±S) group p (X ±S) (X ±S) group P group P
Primary outcome: MFI-20
General fatigue 10.932 ± 2.872 7.341±
3.403
0.000* 10.556 ± 2.896 6.511 ± 2.897 0.000* 0.516
Physical fatigue 10.614 ± 3.674 6.727±
3.172
0.000* 9.067±
3.962
4.511 ± 2.785 0.000* 0.435
Reduced activity 9.818 ± 3.611 6.545±
3.238
0.000* 8.622±
3.6, 200
4.0.911 ± 2.502 0.000* 0.593
Reduced motivation 8.091 ± 3.672 5.114±
2.508
0.000* 8.200±
4.257
4.644 ± 2.854 0.000* 0.482
Mental
fatigue
9.886 ± 3.357 6.318±
2.752
0.000* 10.022 ± 4.104 5.578 ± 2.759 0.000* 0.282
Secondary outcome: PSQI
Total score 7.705 ± 2.953 5.295±
2.378
0.000* 6.756±
3.523
4.200 ± 2.085 0.000* 0.828
Subject sleep quality 1.545 ± 0.697 1.159±
0.079
0.002* 1.444±
0.724
0.956 ± 0.424 0.000* 0.532
Sleep latency 1.705 ± 0.904 1.386±
0.813
0.021* 1.333±
1.066
0.933 ± 0.720 0.011* 0.685
Sleep duration 1.023 ± 0.792 0.409±
0.622
0.000* 0.911±
0.821
0.200 ± 0.405 0.000* 0.609
Habitual sleep efficiency 0.455 ± 0.730 0.364±
0.718
0.439 0.644±
1.171
0.378 ± 0.912 0.209 0.142
Sleep disturbance 1.614 ± 0.618 1.205±
0.461
0.000* 1.467±
0.625
1.022 ± 0.452 0.000* 0.783
Sleep medicine using 0.091 ± 0.473 0.091±
0.291
1.000 0.200±
0.757
0.089 ± 0.468 0.168 0.326
Daytime dysfunction 1.273 ± 0.624 0.682±
0.601
0.000* 1.022±
0.657
0.356 ± 0.609 0.000* 0.593
Secondary outcome: HADS
Anxiety 7.682 ± 3.969 5.727±
3.083
0.000* 7.000±
3.855
4.111 ± 2.113 0.000* 0.198
Depression 6.705 ± 3.927 4.705±
3.069
0.001* 6.844±
4.033
3.444 ± 2.563 0.000* 0.105
*

P < 0.05.